Manual isotopic interference correction — correct_interference

The interference is subtracted using following formula: $$Value_{Corrected} = Value_{Feature} - Factor_{Contribution} * Value_{Interfering Feature}$$

Usage

correct_interference_manual(
  data = NULL,
  variable,
  feature,
  interfering_feature,
  interference_contribution,
  neg_to_na = FALSE,
  updated_feature_id = NA
)

Arguments

data: MidarExperiment object
variable: Default: feature_intensity. Name of Variable to be corrected.
feature: Name of feature to be corrected
interfering_feature: Name of feature that is interfering, i.e. contributing to the signal of feature
interference_contribution: Relative portion of the interfering feature to contribute to the feature signal. Must be between 0 and 1.
neg_to_na: If TRUE, negative or zero values after correction will be replaced with NA. Default: FALSE.
updated_feature_id: Optional. New name of corrected feature. If empty then feature name will not change.

Value

MidarExperiment object