Normalize feature intensities using internal standards

Normalize feature intensities by dividing them by the intensities of the corresponding internal standards (ISTDs). Each feature must have a defined internal standard (ISTD) in the feature metadata.

Usage

normalize_by_istd(data = NULL, ignore_missing_annotation = FALSE)

Arguments

data

A MRMhubExperiment object.

ignore_missing_annotation

If FALSE, the function will raise an error when an ISTD is not defined for one or more features (excluding the ISTDs themselves). If TRUE, features with missing ISTD annotations will have NA values in the normalized intensities.

Value

A MRMhubExperiment object with normalized feature intensities